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Similar content being viewed by others Introduction Vitamin B 9 is one of the crucial vitamins whose physiological function and consequence of its deficiency are well known, however, there is a lack of a comprehensive paper summarizing essential aspects of this vitamin encompassing its natural occurrence, the impact of different factors on its stability and absorption as well as its further fate in the human organism in the context of its possible deficiency with its causes, and consequences, as well as current discussion on possible risks of high dose folate supplementation