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In 2017, the International EDS Consortium revised their diagnostic criteria for all 13 subtypes of EDS, including hypermobile EDS

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Gnathostomiasis is transmitted by the ingestion of third-stage larvae from raw or insufficiently cooked second intermediate or paratenic hosts such as freshwater fish, snakes, poultry, or frogs

Pregnancy and breastfeeding increase B12 requirements, and pregnant women with B12 deficiency may need more frequent monitoring and potentially adjusted treatment schedules

Subsequently statistical analysis was done to look for proportion of patients with a change in etiological classification before and after VW-MRI