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Post-Inflammatory Hyperpigmentation (PIH) This happens when the skin is injured or irritated

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.,FisherAB,ZaniB,HanT,DodiaC,MelidoneRKellerSDecreased LPS-induced lung injury in pigs treated with a lung surfactant protein A-derived nonapeptide that inhibits peroxiredoxin 6 activity and subsequent NOX1,2 activation.2024;326:L458L467

Other pathways implicated, explaining the development of vitiligo, include autophagy and ferroptosis, where oxidative stress impacts the cells ability to clear damaged components, eventually leading to cell death and depigmentation 17,46