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FIGURE 4 11 The role of phytomolecules as an emerging candidate for PD In addition to incretin-mediated effects, several plant-derived phytochemicals target innate immune receptors and inflammatory signaling cascades that contribute to chronic neuroinflammation in both PD and AD (Fiebich et al., 2018)

In contrast, endogenous antioxidant systems are a complex and compartmentalized network that involve controlled and localized production of specific ROS [54]

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induction of fibril formation corresponding to inhibition of membrane interactions is likely the main factor that reduces amyloid protein toxicity by bacoside-A

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