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To identify the selective cargos of V-ATPase-dependent autophagy, we tagged different organellar proteins with GFP at the C-terminal end and performed GFP-processing assays: We found a clear increase in the vacuolar degradation of ribosomal proteins Rps6A and Rpl10, indicating the induction of ribophagy (Fig

Blood tests measuring serum B12 and, if appropriate, methylmalonic acid or homocysteine levels can clarify your B12 status

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Pernicious anemia: This is a condition that develops when the bodys immune system attacks the parietal cells in the stomach that produce intrinsic factor

If your diet includes no or little amounts of these foods, make sure you get your B12 from alternative sources since a B12 deficiency could actually work against you in your effort to lose weight