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The authors suggested that weaker antioxidant functions could intensify oxidative stress and lead to the development of AMD [101]

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Potential users should be aware that while preclinical safety appears excellent, the absence of extensive human clinical trials means unknown risks may exist

Interestingly, despite the presence of superoxide dismutase (SOD) ( k = 2.4 10 9 M 1 s 1 ) 36 , the resulting concentration of H 2 O 2 is significantly smaller than the concentration of superoxide, indicating that the model is able to respond well to a transient increase in ROS, maintaining low H 2 O 2 concentrations