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In a rather representative study, researchers loaded dextran based nanoparticles loaded with the chemotherapeutic drug irinotecan and combined them with engineered phages targeting the tumor-promoting bacterium Fn in experiments using phage-guided nanotechnology to modulate the gut microbiota in mouse models of CRC (Kannen et al., 2019)

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Roozendaal B, Hernandez A, Cabrera SM, Hagewoud R, Malvaez M, Stefanko DP, Wood MA (2010) Membrane-associated glucocorticoid activity is necessary for modulation of long-term memory via chromatin modification