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Tight Junctions as Modulators of Intestinal Integrity and Paracellular Translocation The paracellular transport of important molecules across the intestinal epithelium is regulated by transmembrane and intracellular proteins that interlink to form TJs

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NSAIDs are a common cause of gastric ulcers and intestinal lesions due to their inhibition of prostaglandin synthesis, which is crucial for mucosal defense