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3.4 Metformin and doxorubicin-induced cardiotoxicity Doxorubicin (DOX), a potent anthracycline chemotherapeutic, is widely used in oncology but its clinical utility is limited by dose-dependent cardiotoxicity

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To note, adopting a machine-learning-based classification approach, we found that different classes of progenitor cells express markers of active proliferation in male versus female killifish hematopoietic organs across age groups, which might in principle lead to functional shifts in effector cell abundance and function in either sex

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