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Synthesis of ROS-sensitive polymers (P3) To a solution of ROS sensitive compound (2,2-(propane-2,2-diylbis(sulfanediyl))bis(ehan-1-ol)) (0.26 g, 1.35 mmol) in anhydrous DMF (5 ml), 1,2,4,5-cyclohexanetetracarboxylic dianhydride (0.31 g, 1.41 mmol) was quickly added into the solution

One-quarter of subjects in the placebo group, and none in the glutamine group, developed severe mucositis

Blood samples were collected from dogs administered multiple doses at corresponding time points before the first dosing (0 h), within 6 h after dosing, before the last three doses, and at corresponding time points after the last dosing

Biomarker Insights, 8, 6975

Indeed, the efficacy of melatonin has been tested against the oxygen radical diseases of newborn, giving promising results 100,101,102 (Fig