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Inhibitors of GPX4 effectively trigger iron and lipid peroxidation-dependent cell death, demonstrating considerable antineoplastic effects across various cancers, including nasopharyngeal carcinoma [128], non-small cell lung carcinoma (NSCLC) [129, 130], pancreatic adenocarcinoma [131], and melanoma [132]

Traditional approaches, including surgery, chemotherapy, and radiotherapy, often encounter barriers such as metastasis and adverse effects on healthy tissues

doi: 10.1016/j.apsoil.2003.09.003 45 DalCorsoG.FarinatiS.MaistriS.FuriniA

Standard MS parameters for SureQuant acquisition were as follows: spray voltage: 1.9 kV, no sheath or auxiliary gas flow, heated capillary temperature: 300 C

179 However, in some cases, the downregulation or loss of function of DNMT3B is also related to the occurrence of tumors