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of this final rule with comment period, we specifically proposed that for the purposes of reporting the data on the cost report, hospitals would report the median of the payer-specific negotiated charges for an MS-DRG that the hospital has disclosed for all of its MAOs on the most recent version of the MRF that the hospital is required to disclose under 45 CFR 180.40(a)

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The discontinuation rate in clinical trials ranged between 20% and 50% within the first year, with GI intolerance being the primary reason

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