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Signs and Symptoms of Vitamin B12 Deficiency Vitamin B12 deficiency can present with a wide range of symptoms, many of which develop gradually and may be mistaken for other conditions

It can interfere with many other tests, as well

This often occurs in smokers, people with metabolic disease, heavy alcohol drinkers, as a side effect of certain prescription drugs, rheumatoid arthritis and impaired thyroid function

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In terms of dosage, again, the key is often, daily at least (some of our readers inject twice a day)