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The IM1 and IM2 subsets of interstitial macrophages correspond to the CD206+ that localize in the per-bronchial regions and around vessels, secrete immunoregulatory cytokines and restrain tissue fibrosis and CD206-that localize in the alveolar interstitium and have antigen-presenting roles [37,96,160] respectively as described before

In the open state, VDACs permit the entry of these critical molecules into the mitochondria, facilitating cellular respiration

NFE2L2 (NRF2), nuclear factor erythroid 2-related factor 2

doi: 10.1080/09546630601028778 [DOI] [PubMed] [Google Scholar] 5.Platsidaki E, Efstathiou V, Markantoni V, et al