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After washing with PBS three times, cells were trypsinized and collected

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SHIN1 restores proper proliferation and differentiation programs and reduces inflammatory gene expression in psoriatic skin explants To validate the inhibitory effects of SHIN1 in human disease tissue, lesional skin biopsies from patients with plaque-type psoriasis ( n =5) were cultured ex vivo with or without SHIN1 for 24 h

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