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However, we still believe that this study reveals possible molecular mechanisms underlying UA mediated processes in macrophages that can be related to macrophage infiltration in adipose tissue in obesity

Cells were incubated with a mouse monoclonal antibody targeting the human transferrin receptor (Clone H68.4, #136800, Invitrogen, Eugene, OR) diluted to a final concentration of 2 g/mL in PBS overnight at 4 C

Except for inhibiting oxidative stress-related signaling pathways mediated by Apos, other antioxidative properties of Apos that interact with oxidant and LDL oxidation byproducts are well established

The concentration of these phytochemicals is highly dependent on the environment