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The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins

Aging 33, 13561363

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The obtained results are typical for old animals (Goshovska et al., 2009) and indicate calcium overload of cardiomyocytes, energy deficit, and intensification of oxidative metabolism and support the data about the excessive formation of ROS in aged rat heart mitochondria (Table 2)