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The KYN pathway that produces neurotoxic and neuroinhibitory compounds is regulated by the dopamine metabolites, VMA and HVA, which has been implicated in the pathogenic mechanisms underlying SZ

The percentage of ROS-positive area was significantly higher in the SCI group ( P = 0) and the GlyNAC+SCI group ( P = 0.0036) than in the control group and was significantly higher in the SCI group than in the GlyNAC+SCI group ( P = 0.0076) (Fig

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[,,] Current focused clinical and preclinical research concentrates on glutamate-modulating agents in OCD patients since, currently available treatments for OCD involve drugs that impact the serotonin and dopamine systems, although they are not very helpful in healthcare settings