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8d) and the most significant drop in serum PSA levels (Fig

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Several RNAi drugs, including aptamers like pegaptanib targeting protein targets, and micro interfering RNAs like givosiran and patisiran, as well as antisense oligonucleotides like golodirsen and inotersen that interfere directly with RNA targets, have received FDA approval for medical use (Yu et al., 2020)