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By boosting glutathione levels, either through supplementation or intravenous therapy, patients with Lyme disease may experience enhanced immune function, reduced inflammation, and improved overall well-being, aiding in the recovery process and potentially alleviating some of the debilitating symptoms associated with this chronic condition

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The di-tryptophan cross-link may weaken the non-covalent bonds between the SOD1 monomers, triggering enzyme unfolding, oligomerization, and aggregation (Coelho et al., ALS-associated SOD1 mutants produce free radicals (ONOO or OH ) and some mutants lose its catalytic activity, which in turn produces highly unstable intermediate products and tyrosine (Abe et al., 2006)

(2024) Ergothioneine ameliorates metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) by enhancing autophagy, inhibiting oxidative damage and inflammation

Nature 575:693698 Kim R et al (2022) Ferroptosis of tumour neutrophils causes immune suppression in cancer