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Inhibition of ACSL4 expression or knockdown of LPCAT3 may be key mechanisms for ultimately regulating ferroptosis through different signaling pathways

In conjunction with these mechanisms, the gut microbiota helps maintain immune homeostasis and mitigates the over-activation of immune responses during high-altitude exposure, thereby enhancing the host's adaptation to the plateau environment

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Tevar 19 , Jennifer S

Most chronic diseases of the CNS are associated with loss of function of astrocytes, and such loss of function is emerging as a leading mechanism of disorder-related neurological dysfunctions ranging from mild changes in synapse regulation to potential overt neurotoxicity in extreme cases