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The dose increases at weeks five and nine bring the most challenging side effect periods

DUBs are enzymes that cleave ubiquitin from target proteins and other molecules by hydrolyzing the ester, peptide, or isopeptide bonds at the carboxyl terminus of ubiquitin, thus counteracting ubiquitination-driven protein degradation 19,22,23

Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates

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How do neurexins modulating synaptic plasticity relate upstream and downstream to existing antidepressant mechanisms