foxo4-dri senolytic peptide animal model 2023 2024 ES2 rapidly destroys TP53-FOXO4 foci leading to TP53 mediated Targeting the FOXO4-p53 axis by
Targeting the FOXO4 p53 axis by retro inverso peptide senolytic agents: a pharmacological strategy to mitigate brain aging and cognitive decline Naunyn Schmiedeberg's Archives of Pharmacology Springer Nature Link FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Computational design of peptide targeting FOXO4. a, Domains of FOXO4 Download Scientific Diagram Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment npj Aging Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells ScienceDirect
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