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Long, Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis, Scientific Reports 2016 6:1, vol

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Lindner and colleagues showed that APOE4 astrocytes with ectopic accumulation of fat, a stress-associated condition, had a reduced capacity to clear potentially neurotoxic FAs because APOE4 reroutes them to secretion [132]