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Venous thrombosis (VT) is not uncommon and has a high worldwide disease burden, resulting in mortality in certain cases 9

Punicalagin (CAS 65995-63-3) and punicalin (CAS 65995-64-4) were obtained from BOC Science (Shirley, NY, USA) and Apollo Scientific (Stockport, UK), respectively

These findings show that elevation of pre-rRNA synthesis confers a fitness advantage early in life but accelerates health decline with age, while its restriction limits early life fitness transiently and eventually prolongs both lifespan and healthspan