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doi: 10.3851/IMP3098 42

193 FBXL11, also known as JHDM1A or KDM2A, is the first discovered JmjC domain-containing demethylase, which can demethylate H3K36me1/me2 in a Fe (II) and - ketoglutarate dependent manner

FIGURE 2 4.2 Characteristic analysis of melanin synthetic peptides 4.2.1 Key sites of peptide inhibiting melanin synthesis Peptides inhibit melanin synthesis, mainly by binding with TRP and MITF in melanin biological process

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The majority of research was determined to be at extreme risk of bias due to inadequate description of randomisation (25%, 3/12), allocation concealment (16.67%, 2/12), description of baseline characteristics (8.33%, 1/12), blinding of caregivers/researchers (8.33%, 1/12), selective reporting of results (8.33%, 1/12) and other sources (8.33%, 1/12)