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doi: 10.1111/j.1471-4159.2006.03988.x

15,226,227 Recent therapeutic approaches focus on aldose reductase inhibitors (ARIs), such as epalrestat and ranirestat, which have shown promise in reducing sorbitol accumulation and ameliorating neuropathic symptoms in clinical trials

Sako W, Kogo Y, Koebis M, Kita Y, Yamakage H, Ishida T, et al

Hanson MR, Giloteaux L

Most commonly experienced symptoms of indigestion include a burning sensation, bloating, nausea and vomiting, and other similar problems like heartburn