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These fatty acids are catalyzed by acyl-coenzyme A synthetase long chain family member 4 (ACSL4) and converted to PUFA-coenzyme A (CoA) [31]

These bioactive molecules are capable of modulating key signaling cascades, including the mitogen-activated protein kinase (MAPK) pathway ( While the detrimental impact of heat stress on male semen quality and the beneficial role of L-citrulline in supporting reproductive health are increasingly recognized, robust evidence remains largely confined to preclinical animal and cellular models

IGF-I is equipotent with insulin in stimulating glucose uptake in human muscle but has less effects in fat and liver (92)

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