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Furthermore, the levels of transcortin (or corticosteroid-binding globulin), the primary glucocorticoid-binding protein and a negative control protein, were substantially lower in IMDD patients than in controls [39]

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Changes in cellular NADH/NAD + ratio caused by redox events have recently been reported to alter NQO1 conformation and its ability to bind to or dissociate from target macromolecules 44