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The hydroxylation of IKK serine residues in a prolyl hydroxylase (PHD)-dependent manner may regulate this mechanism [72]

If you are concerned, however, I recommend contacting the supplement manufacturer

And they do a blood test for Lyme, and it doesnt show

Read clinical review A physician-reviewed guide to the losartan and vitamin D interaction, covering pharmacokinetics, pharmacodynamics, dose recommendations, monitoring labs, and safety considerations