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Given the current clinical landscape, the precursor NR is still the most utilized NAD + precursor and regulator overall

ACS Nano 15 , 67096722 (2021)

We thank Philip Creed, PhD, from Edanz ( for editing a draft of this manuscript

That is, we would stop entering patients if, at any time during the study, we estimated that there is more than a 90% chance that the ORR was less than 30%, a constant rate that is slightly above the expected response rate for these patients on other treatments