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proposed that eicosapentaenoic acid (EPA) may exert a therapeutic effect on depression independently, whereas ALA could potentially increase depression risk (165)

Available online at: (Accessed January 07, 2024)

Mechanistically, an expanding body of preclinical/translational research suggests that the gut-microbiome impacts breast carcinogenesis and therapy through several interrelated pathways-chiefly in terms of its estrobolome (microbial pool of genes dedicated to estrogen metabolism), bioactive microbial metabolite synthesis, systemic/mucosal immunity modulation (influencing T-cell subsets/myeloid cell function/inflammatory cytokine networks) also together with drug pharmacokinetics/pharmacodynamics (175)

Back Interviews - unpublished transcripts Lefkovits, Ivan, interviewed by Lara Marks, 6 Aug 2025.Back Lefkovits, Ivan, Waldmann, Herman, interviewed by Lara Marks, 24 June 2025