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We discovered that GPX7 was remarkably increased in glioma tissues and cell lines, and was associated with poor prognosis

When cells experience oxidative stress, Nrf2 dissociates from its repressor, Keap1, moves into the nucleus, and triggers the production of key antioxidant enzymes, such as catalase, superoxide dismutase (SOD), and glutathione peroxidase [35]

Mitochondrial MTHFD isozymes display distinct expression, regulation, and association with cancer

Oakley AJ, Lo Bello M, Battistoni A, Ricci G, Rossjohn J, Villar HO et al

Data availability All data presented in the review paper is published and referenced