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104 In a placebo-controlled trial that included 90 women with menopausal hot flashes, taking 330 mg licorice extract three times daily for eight weeks reduced hot flash frequency and intensity, and the effect did not diminish until two weeks after stopping treatment

Of these two circulating transport proteins, only transcobalamin bound to B12 to form holotranscobalamin (holoTC) in serum is metabolically active, delivering vitamin B12 to receptors on cell membranes

J Neuroendocrinol 11:203209 Karhunen T, Vilim FS, Alexeeva V, Weiss KR, Church PJ (2001) Targeting of peptidergic vesicles in cotransmitting terminals

As a potent biomolecule, GHK-CU acts as a signaling molecule that communicates with various cellular pathways