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Description

Neuropathy is believed to result from pyridoxine neurotoxicity to dorsal root ganglia when plasma levels are excessively high

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The dosage and frequency depend on the severity of the deficiency and the underlying cause

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In C2C12 myotubes, NNMT inhibitor treatment produces concentration-dependent increases in NADH levels (50% higher at 30 M) and reduces NAD+/NADH ratios by 25-40%

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Published studies have shown that NNMT expression affects myogenic differentiation the process by which satellite cells activate, proliferate, and fuse to form new muscle fibers

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