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The recommendations above are based on cyanocobalamin supplements

Vitamin B12 deficiency in young adults without pernicious anemia or dietary cause should prompt evaluation for terminal ileal pathology

What these patients are finding is that as theyve lost quite substantial amounts of weight, its also left them disfigured in certain areas where they have lost real targeted volume, she said over Zoom

When to increase dose Consider increasing if: Minimal response after 4-6 weeks at current dose No side effects at current dose Current dose below the higher end of recommended range Goals not being met with conservative approach Increase gradually, typically by 25-50% at a time