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It has high affinity for heparin and heparin sulfates [17,18]

25 According to research by Wang, Zhu, 26 the inhibitory impact of omega 3 fatty acids on the production of eicosanoids from arachidonic acid is the mechanism by which they prevent the development of cancer

ACh, acetylcholine

In glioblastoma multiforme, the combination of artesunate with lower doses of metformin demonstrates antitumor effects by activating the AMPK/mTOR pathway and inducing autophagy in human glioblastoma (U251 and U118-MG) cells [180]