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Earlier studies have shown that mtDNA heterogeneity and impaired mitochondrial biogenesis occur prior to and during early HF [239, 240]

Numerous studies have underscored the diverse pharmacological activities associated with GBR, including its anti-atherosclerotic, antidepressant, anti-inflammatory, antidiabetic, and hypolipidemic properties, thereby positioning it as a rich source of phytochemicals (Shen et al., 2016)

Tandem mass spectrometry analysis (LC-MS only) was run on the QC samples for identification purposes

Evidence shows minimal prolactin elevation during ipamorelin administration, as demonstrated by head-to-head endocrine comparisons and pituitary secretion studies

Adjustment of pain-modulatory medications can be useful, depending on the background dose