In particular, when homocysteine attached to a protein called syntaxin 17, it blocked the protein from performing its role of transporting and digesting fat (known as autophagy, an essential cellular process by which cells remove malformed proteins or damaged organelles) in fatty acid metabolism, mitochondrial turnover, and inflammation prevention

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This method can bypass potential barriers related to digestion, making it a particularly effective choice for individuals with gastrointestinal disorders or those who have had bariatric surgery
Fast forward to more recent clinical interest in NAD+
After donating one electron, vitamin C forms semidehydroascorbic acid (ascorbate free radical)