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To monitor the transcript level of the trxR gene, the hybridizing probe was amplified from D141 genomic DNA with the primer pair JB064/065 (5-TGTTCTCTATGAGGGTATGC-3 and 5-TTCGACTTGTATTCTGGAACG-3) and labeled during amplification by applying the PCR DIG labeling mix (Roche)

Lipoic acid (LA), also known as alpha-lipoic acid (ALA), R-lipoic acid, or thioctic acid, is a disulfide-containing compound [1], found inside every cell of the body [2]

The following search terms were employed: neuropathic pain,peripheral neuropathy, diabetic neuropathy, postherpetic neuralgia, nerve injury, pain treatment, neuropathic pain management, spontaneous pain, pain sensitization, ion channels, TRPV1, TRPA1, lipid rafts, central sensitization, neuroinflammation, sympathetic nerves, lipoproteins, lipoprotein metabolism, cholesterol, HDL, LDL, VLDL, oxLDL, apolipoproteins, ApoA1, ApoM, PON1, LOX-1 receptor, Lp-PLA2, LPS, TLR4, S1P, PI3K/Akt signaling pathway, ROS, NF-B, LPC, NADPH oxidase, Metabolic Syndrome, lipotoxicity, endotoxemia, lipid-lowering therapy, Statins, acetyl-l-carnitine, pyridoxine, quercetin

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