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In neurodegenerative contexts, mitochondrial Ca 2+ dysregulation can trigger opening of the mitochondrial permeability transition pore (mPTP), leading to membrane depolarization, swelling, and apoptotic or necrotic death

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A practical translational approach involves coordinated ophthalmology-endocrinology-rehabilitation care pathways, in which structured exercise programs are integrated with routine ocular and metabolic management

If you drink greater amounts of alcohol, the metabolites, such as acetaldehyde, start to accumulate and cause damage to cells

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