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To confirm that haem-assisted dimerization of PGRMC1 occurs in solution, we analysed the structure of apo- and haem-bound PGMRC1 by two-dimensional nuclear magnetic resonance (NMR) using heteronuclear single-quantum coherence and transverse relaxation-optimized spectroscopy (Supplementary Figs 6b and 7)

However, it should be noted that other free amino acids, which are present in the blood serum at total 3 mM concentration 42 , can also form tight ternary complexes with Cu(II)-His 45

Unlike the GN induced ARF group, rats administered CS or spanlastics exhibited no significant alterations in the levels of KIM-1 and NGAL in their tissues

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