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doi:10.1515/bchm2.1932.210.1-2.33

In addition, we used the following genetically engineered mouse strains from the Jackson Laboratory: Rosa26 mT/mG (RRID:IMSR_JAX:007676) 83 , Rosa26 M2rtTA /TetO-H2BGFP mice 84 , doubly transgenic for a reverse tetracycline-controlled transactivator (rtTA-M2) targeted to the Rosa26 locus and a HIST1H2BJ/EGFP fusion protein (H2BGFP) expressed from a tetracycline promoter element (RRID:IMSR_JAX:005104) 24,85 , multicolor reporter line Rosa26 tm1(CAG-Brainbow2.1)Cle ( R26-confetti , RRID:IMSR_JAX:017492) 86 Rosa26 flYFP/flYFP mice (R26-YFP, RRID:IMSR_JAX:006148) 87 , Rosa26 nT/nG (RRID:IMSR_JAX:023035), Nfe2l2 tm1Ywk (RRID:IMSR_JAX:017009), Rosa26 Cas9-P2A-EGFP (RRID:IMSR_JAX:024858) 63 , Notch1 fl/fl (RRID:IMSR_JAX:007181) 88 , LSL Kras +/ G12D (RRID:IMSR_JAX:019104) 83 and Rosa26 flDNM-GFP/wt (RRID:IMSR_JAX:032613 R26-DNM ) 60,89

None of that evidence, though, separates the technique from its aftercare, because the procedure opens a door, and what happens next is what decides whether the result is the smooth, even skin you wanted or a flare of irritation and pigment you did not

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