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1 H NMR (500 MHz, DMSO) 7.95 (t, J = 38.4 Hz, 5H), 7.41 (p, J = 5.1, 3.9 Hz, 18H), 7.23 (d, J = 7.4 Hz, 2H), 7.09 (d, J = 7.4 Hz, 12H), 6.96 (d, J = 19.0 Hz, 2H), 6.70 (q, J = 9.2, 8.1 Hz, 4H), 4.56 (d, J = 54.2 Hz, 2H), 4.18 (d, J = 69.9 Hz, 3H), 3.56 (tt, J = 18.3, 9.3 Hz, 7H), 3.03 2.77 (m, 10H), 1.66 1.20 (m, 54H)

The shaft and lever lock together and are held in place via a small screw which is hidden from all but the most curious

Ferroptosis is driven by iron-dependent lipid peroxidation, primarily initiated by glutathione (GSH) depletion or inactivation of GSH peroxidase 4 (GPX4)