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This makes hCG the preferred tool in preclinical models requiring sustained LHCGR stimulation rather than pulsatile receptor engagement

Some portion of intranasally administered peptides may reach the brain through the olfactory pathway, bypassing the blood-brain barrier that limits systemic delivery to CNS tissues

For people with a vitamin B12 deficiency in the early stages of pregnancy, the child is at an increased risk of neural tube birth defects (birth defects that affect your babys brain, spine, or spinal cord) and low birth weight

The accuracy of the predicting values also needs to be validated in a future study involving a larger population

Clinical evidence for this mechanism in humans is limited