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Sie sind an der Herstellung von Steroidhormonen beteiligt (Testosteron, strogen, Cortisol)

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These molecules undergo subsequent reactions to form highly reactive hydroxyl radicals and cytotoxic ROS

Although the rate constants associated with the binding of NADPH are not defined in this analysis, estimates of the K NADPH could be obtained when the NADPH concentration series was fit for both the C159S and U597S variants (Figure 3C