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Metabolism (2016) 65(8):103848

(2020) discovered that oroxylin A could boost peroxisome proliferator-activated receptor gamma coactivator 1 alpha/mitofusin 2 (PGC-1/Mfn2) signaling, reduce ROS accumulation, prevent NLRP3 inflammasome activation, and block the classical caspase-1-dependent pyroptotic pathway, thereby reducing alcohol-induced liver cell damage