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This oxidative stress is linked to various chronic diseases, including heart disease, cancer, and neurodegenerative conditions

This data suggests that while lower doses (5-15g) are excellent for maintenance and mild IBS, repairing severe, pathological "leaky gut" may require transient, high-dose interventions under medical supervision to rapidly force the reassembly of tight junction proteins

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However, dietary lipid supplementation improves neurological deficits caused by the lack of lipid generation by astrocytes 106

Future studies should focus on early intervention, ideally within the first 612 h of ICU admission, to maximize its potential benefits