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The physiological functioning of fish degraded, ranging from gross clinical signs to deep-rooted neural, immunological, and endocrine disruptions, ultimately leading to reduced growth, reproductive failure, and population collapse (Figure 2)

NSAIDs NSAIDs inhibit cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby inflammation and pain

Further, pretreatment with quercetin and acetazolamide helps in restoration of Cl ions efficiently when compared with hypoxia exposed group

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By raising mitochondrial respiration and oxidative phosphorylation, glucocorticoids directly cause neuronal OS (62)