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Accumulating clinical and experimental evidence confirms ferroptosis as a pivotal driver of kidney disease onset and progression

This can promote inflammation and autoimmunity

While animal studies suggest a favorable safety profile, comprehensive human safety data is lacking

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Leaky Gut As a Danger Signal for Autoimmune Diseases Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers Resveratrol Protects against TNF--Induced Injury in Human Umbilical Endothelial Cells through Promoting Sirtuin-1-Induced Repression of NF-KB and p38 MAPK Impaired Intestinal Permeability Contributes to Ongoing Bowel Symptoms in Patients With Inflammatory Bowel Disease and Mucosal Healing